Publications and on-line resources arising from the project and links and references for other relevant publications:
Basic introduction to COPD
Good simple What is COPD video on You-tube from European COPD Coalition.
- Education about tobacco dependence in Uganda - as part of lung health education funded by Global Bridges
FRESH AIR publications
All publications resulting from the FRESH AIR Horizon 2020 will be published using Open Access.
- Cragg L, Williams S, Chavannes NH on behalf of the FRESH AIR Group. FRESH AIR: an implementation research project funded through Horizon 2020 exploring the prevention, diagnosis and treatment of chronic respiratory diseases in low-resource settings. Npj Prim Care Respir Med [Internet];2016 Jun 30;26:16035. Available from:http://rdcu.be/twwC
IPCRG 2018 (forthcoming www.ipcrg2018.org - still time time register)
|Anastasaki, Marilena||Terms, concepts, barriers and treatment practices towards childhood cough and asthma in rural Greece: a qualitative FRESH AIR study.|
|Brakema, Evelyn||Critical factors to the implementation of interventions targeting chronic lung disease in lower-resource settings – a FRESH AIR systematic review|
|Brakema, Evelyn||More household air pollution and COPD at higher altitude - a population-based, observational FRESH AIR study in rural Kyrgyzstan|
|Brakema, Evelyn||The silent economic impact of chronic lung diseases in low-resource settings in Africa, Asia and Europe – a FRESH AIR study|
|Isaeva, Elvira||Antibiotics prescribed by health care workers for children under 5 years with respiratory symptoms in rural areas in Kyrgyz Republic. A FRESH AIR study.|
|Jones, Rupert||The 5 steps leaflet: a patient guide to managing their COPD developed in the FRESH AIR programme|
|Katagira, Winceslaus||Feasibility of conducting an internet-based Spirometry training for health care workers in Uganda: The Fresh Air Horizon 2020 experience|
|Kjærgaard, Jesper||FRESH AIR: Assessment and treatment of acute respiratory illness in children under 5 in primary care in low- and middle-income settings: An observational study.|
|Le An, Pham||Translating an internet-based spirometry training for health care practitioners in Vietnam:The FRESH AIR H2020 experience|
|Østergaard, Marianne Stubbe||Asthma in children under 5 years in rural Kyrgyzstan - a diagnostic vacuum? A qualitative FRESH AIR study|
|Østergaard, Marianne Stubbe||Diagnostic terminology used for young children with recurrent lower respiratory illness in rural Greece, Kyrgyzstan and Uganda. A comparative FRESH AIR study|
|Østergaard, Marianne Stubbe||Recurrent lower respiratory illnesses among young children in rural Kyrgyzstan: Overuse of antibiotics. A qualitative FRESH AIR study|
|Papadakis, Sophia||Training general practitioners in Greece in ‘Very Brief Advice’ on smoking: The FRESH AIR Project|
|Sooronbaev, Talant||Feasibility and effectiveness of training program in Very Brief Advice for smoking for GPs and Family doctors in Kyrgyz Republic — a FRESH AIR study|
|Stout, James||Implementing multiple interventions to improve respiratory care & health in resource-constrained FRESH AIR countries: Impact, Barriers, Levers & Lessons Learned|
|Stout, James W.||Delivering internet-based spirometry training for health care workers in four countries: The FRESH AIR H2020 experience|
|Stout, James W.||Efforts to implement a novel smart-phone spirometer in four countries: The FRESH AIR H2020 experience|
|Vogler, Kristoffer||The effect on knowledge and practice of training rural health care workers in treating asthma in children under five. A FRESH AIR study.|
|Jones, Rupert||Implementing of Pulmonary rehabilitation in Vietnam, preliminary results.|
|Cartwright, Lucy||An implementation strategy for a midwife-led education programme of biomass smoke reduction among pregnant women and postnatal mothers in Uganda|
|Pooler, Jillian||Adapting and implementing very brief advice on smoking to save lives in low and middle-income countries - FRESH AIR|
|Emilov, Berik||Indoor air pollution and effectiveness new clean cookstoves in highland Naryn region of Kyrgyzstan|
|Katagira, Winceslaus||Feasibility of conducting an internet-based Spirometry training for health care workers in Uganda: The Fresh Air Horizon 2020 experience|
|Mademilov, Maamed||The awareness-raising programme and testing knowledge among rural population about damaging effects of indoor air pollution and tobacco smoking in Kyrgyzstan|
- Brakema E, van der Kleij R, Poot C, Cragg L, Williams S, Numans M, et al. Beliefs and behaviours towards chronic lung disease - a mixed-method FRESH AIR study. Eur Respir J [Internet]. 2017 Sep 1;50(suppl 61). Available from: http://erj.ersjournals.com/content/50/suppl_61/PA3891.abstract
- Van Boven JFM, Brakema EA, Walusimbi S, Anastasaki M, Tabyshova A, Nguyen L, et al. Late Breaking Abstract - Health economic burden of asthma/COPD in Uganda, Vietnam, Kyrgyzstan and Greece: FRESH AIR results. Eur Respir J [Internet]. 2017 Sep 1;50(suppl 61). Available from: http://erj.ersjournals.com/content/50/suppl_61/OA2911.abstract
- Tabyshova A, Emilov B, Seiitov M, Beyshenbekova A, Osmonov B, Estebesova B, et al. Indoor air pollution and respiratory symptoms, and pneumonia in highland children in Kyrgyzstan. Eur Respir J [Internet]. 2017 Sep 1;50(suppl 61). Available from: http://erj.ersjournals.com/content/50/suppl_61/PA1859.abstract
- van Gemert F, Kirenga B, Jones R, Williams S. The development and implementation of a lung health awareness programme in a rural district of Uganda. Eur Respir J [Internet]. 2017 Sep 1;50(suppl 61). Available from: http://erj.ersjournals.com/content/50/suppl_61/PA3895.abstract
- CR37. Tsiligianni I et al. Qualitative evaluation of a pulmonary rehabilitation programme in Greece: results from the FRESH AIR project
- RI01. Brakema EA. Beliefs and behaviours towards chronic lung disease - a mixed-method FRESH AIR study
- RI03. Brakema EA. Epidemiological features and economic burden of COPD in Vietnam – a FRESH AIR study
- CR37. Tsiligianni I. Qualitative evaluation of a pulmonary rehabilitation programme in Greece: results from the FRESH AIR project.
Policy: WHO-GARD recognition
Khaltaev N. GARD, a new way to battle with chronic respiratory diseases, from disease oriented programmes to global partnership. J Thorac Dis 2017;9(11):4676-4689. doi: 10.21037/jtd.2017.11.91. Available: http://jtd.amegroups.com/article/view/17245/pdf
Latest papers from our team
- Rapid assessment of the demand and supply of tobacco dependence pharmacotherapy in Uganda. Kirenga BJ, Jones R, Muhofa A, Nyakoojo G, Williams S. Rapid assessment of the demand and supply of tobacco dependence pharmacotherapy in Uganda. 2016;I(1):35–7.
- IPCRG 5th Scientific Meeting May 2017: CR21. Nantanda R. Health workers’ practices in management of respiratory illnesses among ‘under-fives’ in primary care settings in Uganda: a descriptive study.
- RI06. Tsiligianni I. TiTAN Greece & Cyprus – Primary Care Tobacco Treatment TrAining Network in Greece & Cyprus
Studies from the original IPCRG FRESH AIR programme:
- Page summarising original FRESH AIR work in Uganda, including link to PhD thesis of Frederik van Gemert
- Final publication from Uganda prevalence survey and editorial in Lancet Global Health van Gemert F et al. Prevalence of chronic obstructive pulmonary disease and associated risk factors in Uganda (FRESH AIR Uganda): a prospective cross-sectional observational study. Lancet Glob Health 2015; 3: e44–51 DOI: http://dx.doi.org/10.1016/S2214-109X(14)70337-7
- Editorial Salvi S. The silent epidemic of COPD in Africa. The Lancet Global Health, Volume 3 , Issue 1 , e6 - e7 DOI: http://dx.doi.org/10.1016/S2214-109X(14)70359-6
- van Gemert et al, Impact of asthma and COPD in sub-Saharan Africa, Prim Care Respir J 2011, 20(3):240-248
- van Gemert F, Chavannes N, Nabadda N, Luzige S, Kirenga B, Eggermont C, de Jong C, van der Molen T. Impact of chronic respiratory symptoms in a rural area of sub-Saharan Africa: an in-depth qualitative study in the Masindi district of Uganda. Prim Care Respir J 2013;22(3):300-305. DOI: http://dx.doi.org/10.4104/pcrj.2013.00064
- ERS 2014 E-poster: Prevalence of COPD in sub-Saharan Africa: FRESH AIR Uganda survey
- ERS 2013 poster: Prevalence of COPD and its risk factors in a rural area of Uganda: FRESH AIR Uganda
- World Health Organization Implementation Science Toolbox: http://www.who.int/tdr/publications/year/2014/ir-toolkit-manual/en/
- Global Burden of Disease infographics: http://vizhub.healthdata.org/gbd-compare/
- Health at a Glance OECD indicators: http://www.oecd-ilibrary.org/social-issues-migration-health/health-at-a-glance_19991312
- Global Health Trials: https://globalhealthtrials.tghn.org/
- Nature Partner Journals Primary Care Respiratory Medicine education and translated articles Do research
World Health Organization 2015. Reducing global health risks through mitigation of short-lived climate pollutants. Scoping report for policymakers on short-lived climate pollutants (SLCPs), including black carbon, methane, and ozone, are responsible for a substantial fraction of climate change as well as for a significant proportion of air-pollution related deaths and diseases that kill some 7 million people per year.
As the project progresses, you will be able to access an extensive bibliography of published articles, grey literature and useful websites prepared by the consortium.
Respiratory disease globally
Forum of International Respiratory Societies. The Global Impact of Respiratory Disease – Second Edition. Sheffield, European Respiratory Society, 2017. Available from: https://www.firsnet.org/publications/the-global-impact-of-respiratory-disease
Townend J, Minelli C, Mortimer K, Obaseki DO, Al Ghobain M, Cherkaski H, et al. The association between chronic airflow obstruction and poverty in 12 sites of the multinational BOLD study. Eur Respir J [Internet]. 2017 Jun 1;49(6). Available from: http://erj.ersjournals.com/content/49/6/1601880.abstract
Early lung development and impact on the development of COPD
Alexander DA, Northcross A, Karrison T, Morhasson-Bello O, Wilson N, Atalabi OM, et al. Pregnancy outcomes and ethanol cook stove intervention: A randomized-controlled trial in Ibadan, Nigeria. Environ Int [Internet]. Elsevier; 2018;111(July 2017):152–63. Available from: https://doi.org/10.1016/j.envint.2017.11.021
UNICEF. Clear the Air for Children. The impact of air pollution on children. October 2017. Available from https://www.unicef.org/publications/files/UNICEF_Clear_the_Air_for_Children_30_Oct_2016.pdf
Sly PD. From the Cradle to the Grave : The Early-Life Origins of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016;193:1–3
Martinez FD. Early-Life Origins of Chronic Obstructive Pulmonary Disease. N Engl J Med [Internet]. 2016;375(9):871–8. Available from: http://www.nejm.org/doi/10.1056/NEJMra1603287
Bush A, Bolton CE. Longer Term Sequelae of Prematurity: The Adolescent and Young Adult. In: Hibbs AM, S. MM, editors. Respiratory Outcomes in Preterm Infants: From Infancy through Adulthood [Internet]. Cham: Springer International Publishing; 2017. p. 99–118. Available from: http://dx.doi.org/10.1007/978-3-319-48835-6_7 . (with extensive open source reference list)
Gray D, Willemse L, Visagie A, Czövek D, Nduru P, Vanker A, et al. Determinants of early-life lung function in African infants. 2017;445–50.http://thorax.bmj.com/content/72/5/445
Lange P, Celli B, Agustí A, Boje Jensen G, Divo M, Faner R, et al. Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease. N Engl J Med [Internet]. Massachusetts Medical Society; 2015 Jul 8;373(2):111–22. Available from: http://dx.doi.org/10.1056/NEJMoa1411532
Barker P. Relation of birth weight and childhood respiratory infection to adult. 1991;303:671–5. Available from: http://www.bmj.com/content/303/6804/671.full.pdf+html
Lawlor DA, Ebrahim S, Smith GD. Association of birth weight with adult lung function: findings from the British Women’s Heart and Health Study and a meta-analysis. 2005;i:851–8. Available from: http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1747204&blobtype=pdf
Kotecha SJ, Edwards MO, Watkins WJ, Henderson AJ, Paranjothy S, Dunstan FD, et al. Effect of preterm birth on later FEV1: a systematic review and meta-analysis. Thorax [Internet]. 2013 Aug 1;68(8):760–6. Available from: http://thorax.bmj.com/content/68/8/760.abstract
Svanes C, Sunyer J, Plana E, Dharmage S, Heinrich J, Jarvis D, et al. Early life origins of chronic obstructive pulmonary disease. 2010;14–20. Available from: http://thorax.bmj.com/content/65/1/14.full.pdf+html
Tai A, Tran H, Roberts M, Clark N, Wilson J, Robertson CF. The association between childhood asthma and adult chronic obstructive pulmonary disease. Thorax [Internet]. 2014 Mar 19; Available from: http://thorax.bmj.com/content/early/2014/03/19/thoraxjnl-2013-204815.abstract
Task-shifting and task-sharing
Maher D, Cometto G. Research on community-based health workers is needed to achieve the sustainable development goals. Bulletin of the World Health Organization 2016;94:786. doi: http://dx.doi.org/10.2471/BLT.16.185918
Joshi R, Alim M, Kengne AP, Jan S, Maulik PK, Peiris D, et al. Task shifting for non-communicable disease management in low and middle income countries - A systematic review. PLoS One. 2014;9(8).
Praveen D, Patel A, McMahon S, Prabhakaran D, Clifford GD, Maulik PK, et al. A multifaceted strategy using mobile technology to assist rural primary healthcare doctors and frontline health workers in cardiovascular disease risk management: protocol for the SMARTHealth India cluster randomised controlled trial. Implement Sci [Internet]. 2013;8:137. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4222027&tool=pmcentrez&rendertype=abstract
Fairall L, Bateman E, Cornick R, et al. Innovating to improve primary care in less developed countries: towards a global model. BMJ Innov. 2015;1:196-203.
Fairall LR, Folb N, Timmerman V, Lombard C, Steyn K, Bachmann MO, Bateman ED, Lund C, Cornick R, Faris G, Gaziano T, Georgeu-Pepper D, Zwarenstein M, Levitt NS. Educational outreach with an integrated clinical tool for nurse-led non-communicable chronic disease management in primary care in South Africa: a pragmatic cluster randomized controlled trial. PLOS Med 2016; 13(11):e1002178. doi:10:1371/journal.pmed.1002178
Bateman ED. Integrated clinical management tools for respiratory diseases: lessons from PAL in sub-Saharan Africa. Int J Tuberc Lung Dis. 2016 Apr;20(4):429. doi: 10.5588/ijtld.16.0116
Petersen I, Fairall L, Egbe CO, Bhana A. Optimizing Lay Counsellor Services for Chronic Care in South Africa: A Qualitative Systematic Review. Patient Education and Counselling. Patient Educ Couns. 2014 May;95(2):201-10
Barton GR, Fairall L, Bachmann MO, Uebel K, Timmerman V, Lombard C, Zwarenstein M. Cost-effectiveness of nurse-led versus doctor-led antiretroviral treatment in South Africa: pragmatic cluster randomised trial. 2013;18(6):769-77. doi: 10.1111/tmi.12093.
Fairall LR, Bachmann MO, Lombard C, et al. Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH): a pragmatic, parallel, cluster-randomised trial. Lancet. 2012;380:889–98.
Georgeu D, Colvin CJ, Lewin S, et al. Implementing nurse-initiated and managed antiretroviral treatment (NIMART) in South Africa: qualitative process evaluation of the STRETCH trial. Implement Sci. 2012; 7:66.
Mash B, Fairall LR, Adejayan O, Ikpefan O, Kumari J, Mathee S, Okun R, Yogolelo W. A morbidity survey of South African primary care. Plos Medicine. PLoS One. 2012;7(3):e32358.
Zwarenstein M, Fairall LR, Lombard C, et al. Outreach education for integration of HIV/AIDS care, antiretroviral treatment, and tuberculosis care in primary care clinics in South Africa: PALSA PLUS pragmatic cluster randomised trial. BMJ. 2011;342:d2022.
Additional PACK references
Rianne van der Kleij
Pollution and health
- Alexander DA, Northcross A, Karrison T, Morhasson-Bello O, Wilson N, Atalabi OM, et al. Pregnancy outcomes and ethanol cook stove intervention: A randomized-controlled trial in Ibadan, Nigeria. Environ Int [Internet]. Elsevier; 2018;111(July 2017):152–63. Available from: https://doi.org/10.1016/j.envint.2017.11.021
- Sinharay R, Gong J, Barratt B, Ohman-Strickland P, Ernst S, Kelly F, et al. Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study. Lancet [Internet]. Elsevier; 2018 Jan 8; Available from: http://dx.doi.org/10.1016/S0140-6736(17)32643-0
- WHO. Preventing Noncommunicable Diseases (NCDs) Reducing Environmental Risk Factors. 2017; Available from: http://apps.who.int/iris/bitstream/10665/258796/1/WHO-FWC-EPE-17.01-eng.pdf?ua=1
- Watts N, Amann M, Ayeb-Karlsson S, Belesova K, Bouley T, Boykoff M, et al. The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health. Lancet [Internet]. 2017;6736(17). Available from: http://linkinghub.elsevier.com/retrieve/pii/S0140673617324649
- Landrigan PJ, Fuller R, Acosta NJR, Adeyi O, Arnold R, Basu N (Nil), et al. The Lancet Commission on pollution and health. Lancet [Internet]. 2017;6736(17). Available from: http://linkinghub.elsevier.com/retrieve/pii/S0140673617323450
- M, Schoufour J, Freak-Poli R, Koolhaas CM, Dhana K, Bramer WM, et al. Levels of ambient air pollution according to mode of transport: a systematic review. Lancet Public Heal [Internet]. The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND license; 2017;2(1):e23–34. Available from: http://dx.doi.org/10.1016/S2468-2667(16)30021-4
- Neira M, Pfeiffer M, Campbell-Lendrum D, Prüss-Ustün A. Towards a healthier and safer environment. Lancet [Internet]. 2017;6736(17):1–2. Available from: http://linkinghub.elsevier.com/retrieve/pii/S014067361732545X
- Anderson HR. Implications for the science of air pollution and health. Lancet Respir Med [Internet]. Elsevier Ltd; 2017;6736(17):4–5. Available from: http://linkinghub.elsevier.com/retrieve/pii/S221326001730396X
- Das P, Horton R. Pollution, health, and the planet: time for decisive action. Lancet [Internet]. Elsevier Ltd; 2017;6736(17):1–2. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0140673617325886
- Gordon S, Mortimer K, Grigg J, Balmes J. In control of ambient and household air pollution — how low should we go? Lancet Respir Med [Internet]. Elsevier Ltd; 2017;2600(17):10–1. Available from: http://linkinghub.elsevier.com/retrieve/pii/S2213260017303934
Recommended implementation Science papers
- Pinnock H, Sheikh A. Standards for reporting implementation studies ( StaRI ): enhancing reporting to improve care. npj Prim Care Respir Med [Internet]. Springer US; 2017;(May):1–2. Available from: http://dx.doi.org/10.1038/s41533-017-0045-7
- Pinnock H, Barwick M, Carpenter CR, Eldridge S, Grandes G, Griffiths CJ et al. Standards for Reporting Implementation Studies (StaRI) Statement BMJ 2017; 356 :i6795. Available at: http://www.bmj.com/content/356/bmj.i6795
- Pinnock H, Barwick M, Carpenter CR for the StaRI Group, et al Standards for Reporting Implementation Studies (StaRI): explanation and elaboration document BMJ Open 2017;7:e013318. doi: 10.1136/bmjopen-2016-013318. Available at: http://bmjopen.bmj.com/content/7/4/e013318.citation-tools
- Moore GF, Audrey S, Barker M, Bond L, Bonell C, Hardeman W, et al. Process evaluation of complex interventions : Medical Research Council guidance. :1–7. Available from: http://www.bmj.com/content/350/bmj.h1258
- Bauer, MS, Damschroder L, Hagedorn H, Smith J, Kilbourne AM. 2015. An introduction to implementation science for the non-specialist. BMC Psychology 3 (1): 32. doi:10.1186/s40359-015-0089-9.
- Hawe P. Lessons from Complex Interventions to Improve Health. Annu Rev Public Health [Internet]. Annual Reviews; 2015 Mar 18;36(1):307–23. Available from: http://dx.doi.org/10.1146/annurev-publhealth-031912-114421
- Hawe P, Shiell A, Riley T. Theorising Interventions as Events in Systems. Am J Community Psychol [Internet]. 2009;43(3):267–76. Available from: http://dx.doi.org/10.1007/s10464-009-9229-9
Tomoaia-cotisel A, Scammon DL, Waitzman NJ, Cronholm PF, Driscoll DL, Solberg LI, et al. Context Matters : The Experience. Ann Fam Med. 2013;11(Supp 1):115–23.
- Hales S, Lesher-trevino A, Ford N, Maher D, Tran N. Reporting guidelines for implementation and operational research. Bull World Heal Organ. 2016;94(November 2015):58–64.
- World Health Organization/TDR. 2014. Implementation research toolkit. Geneva, Switzerland: World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases. http://www.who.int/tdr/publications/year/2014/9789241506960_workbook_eng.pdf
- Glandon D, Paina L, Alonge O, Peters DH, Bennett S. 10 Best resources for community engagement in implementation research. Health Policy Plan [Internet]. 2017;(November):1–9. Available from: http://academic.oup.com/heapol/article/doi/10.1093/heapol/czx123/4582360
Evidence-based medicine resources
Academy of Medical Royal Colleges, UK, 2017, resources on How can we enhance the use of scientific evidence?http://acmedsci.ac.uk/policy/how-can-we-all-best-use-evidence
Teaching EBM to school-children in Uganda. See http://www.informedhealthchoices.org/primary-school-resources/ and report of RCT in Lancet
Evidence based medicine manifesto for better healthcare http://www.bmj.com/content/357/bmj.j2973
PACK programmes developed by the Knowledge Translation Unit, South Africa.
The University of Leeds, UK has built a list of databases and websites from around the world where randomised controlled trials have been found. Link: http://medhealth.leeds.ac.uk/info/639/information_specialists/1790/finding_randomised_controlled_trials
It lists clinical trials and research study websites and registries, international databases, regional and national databases. It indicates which ones are freely available and those containing open access to free full text articles.
It has not been checked since 2016.
Global Health Trials https://globalhealthtrials.tghn.org/ "This web-based facility has been developed by a collaboration between many research organisations (listed below) that work in the field of global health. It is open access and free. The ethos of this initiative is that those working on trials in resource limited setting can access each other; whatever their role and whatever disease they work on. Researchers can then work together to share guidance, tools and resources in order to improve trials and make them easier to conduct, thereby helping address questions around diseases of poverty. This site also provides guidance material, standard documents and training resources."
Participatory Ethnographic Evaluation and Research (PEER) http://www.options.co.uk/peer "It is an innovative approach to qualitative research. It was developed by Options experts, in collaboration with Swansea University. Members of a community (PEER researchers) are trained to carry out in-depth conversational interviews with friends in their social networks. By working with established relationships of trust between friends, PEER generates rich insights into how people view their world, and how they make decisions on key issues. The PEER process enables programmes to engage communities in discussions, and ensures that the views of marginalised and disadvantaged groups can be heard.
PEER is designed to be rapid, easy to replicate, and useful in a wide variety of different settings. Over the last ten years, in countries across Africa, Asia, Latin America and the Caribbean, and in the UK".